STUDY OF MACULAR THICKNESS, MICRO-VASCULAR, AND PERI PAPILLARY NERVE FIBER LAYER THICKNESS CHANGES AFTER UNCOMPLICATED PHACOEMULSIFICATION IN DIABETIC AND NON DIABETIC PATIENTS

Document Type : Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations

Authors

Ophthalmology dept., Faculty of Medicine, Alazhar Univ, Assuit., Egypt

Abstract

Background: phacoemulsification continues to be one of the most popular surgical procedures
for cataract extraction in the ophthalmologic practice. Optical Coherence Tomography (OCT) is
a noninvasive and noncontact diagnostic tool with high resolution to assess macular changes.
Aim of the study: evaluate changes in macular thickness, micro vascular changes and peri
papillary NFL thickness that occur after uncomplicated phacoemulsification surgery in eyes with
and without DR in diabetic patients and in a control group.
Methods: This study was designed
as Prospective, non-randomized study controlled clinical trial. included 100 eyes
. Included Diabetic
and non-diabetic patients were scheduled for phacoemulsification surgery with intraocular lens
(IOL) implantation included divided into four groups: control group, non-diabetic, diabetic with no
DR, diabetic with mild -moderate NPDR, diabetic with severe NPDR. The central retinal (foveal)
thickness microvascular changes & peripapillary NFL thickness of all patients measured with OCT
one week and 1, 3, and 6 months after surgery. A fundus examination with full pupil dilation performed during each scheduled examination.
Results: There was non-significant difference in
central macular thickness CMT, RNFL after one month there was a significant difference between
groups while after 3 & 6 months the difference was highly significant. Regarding visual acuity
evaluation there was significant difference between different groups at preoperative and after
1week in the BCVA, also there was moderate significant difference between different groups
after 1month, 3months & 6months.
Conclusion: cataract phacoemulsification cause increase in
CMT, RNFL thickness and SCP values in diabetic with different severities of retinopathy.


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